Mitochondrial Dynamics in Cellular Senescence

Authors

  • Cameron Campbell PhD
  • Ava Baker Dr.
  • Nico Phillips Prof.

Keywords:

Mitochondrial dynamics, Cellular senescence, Fusion and fission, Aging, Therapeutic targets

Abstract

This study explores the role of mitochondrial dynamics in cellular senescence, focusing on the balance between mitochondrial fusion and fission. Using advanced imaging techniques, we observed alterations in mitochondrial morphology that correlate with senescence markers in various cell types. Our findings suggest that mitochondrial dynamics play a critical role in the regulation of cellular aging and may serve as potential targets for therapeutic interventions. These insights contribute to a deeper understanding of mitochondrial function in the aging process.

Author Biographies

Cameron Campbell, PhD

PhD
Harvard University
Cambridge, MA, USA

Ava Baker, Dr.

Dr.
University of Oxford
Oxford, OX1 2JD, UK

Nico Phillips, Prof.

Prof.
University of Sydney
Sydney, NSW 2006, Australia

References

Kumar, R. V., Sharma, V. K., Chattopadhyay, B., & Chakraborty, S. (2012). An improved plant regeneration and Agrobacterium-mediated transformation of red pepper (Capsicum annuum L.). Physiology and Molecular Biology of Plants, 18(4), 357-364.

Sharma, V.K.; Marla, S.; Zheng, W.; Mishra, D.; Huang, J.; Zhang, W.; Morris, G.P.; Cook, D.E. CRISPR guides induce gene silencing in plants in the absence of Cas. Genome Biol. 2022, 23, 6.

Published

2024-12-18

Issue

Section

Articles