Autophagic Flux Modulation in Oncogenic Stress: A Case Study Using Advanced Live-Cell Imaging Techniques in Triple-Negative Breast Cancer Cells
Keywords:
Autophagic Flux, Oncogenic Stress, Live-Cell Imaging, Triple-Negative Breast Cancer, Chemoresistance, Targeted Therapy, Cellular Homeostasis, Cancer Pathophysiology, Drug ResistanceAbstract
This study explores the dynamics of autophagic flux modulation in response to oncogenic stress within triple-negative breast cancer (TNBC) cells. Utilizing advanced live-cell imaging techniques, we observed significant alterations in autophagic activity, providing insights into cellular survival mechanisms. Our findings indicate that TNBC cells exhibit a unique autophagic response, potentially contributing to chemoresistance. Understanding these mechanisms paves the way for developing targeted therapies to overcome drug resistance in aggressive breast cancer subtypes.
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