Autophagy and Cell Death in Neurodegenerative Diseases

Abstract

This paper examines the processes of autophagy and programmed cell death (apoptosis) in the context of neurodegenerative diseases such as Alzheimer's and Parkinson's. Through the use of animal models and cell culture experiments, we delineated how dysfunctional autophagy contributes to neuronal death. By targeting key regulatory pathways, potential therapeutic strategies were proposed to enhance autophagic activity, thereby reducing neurodegeneration. These insights pave the way for novel treatment approaches.