Endoplasmic Reticulum Stress and Cancer Cell Survival

Authors

  • Ashley Young
  • Pat Young
  • Kim Clark

Keywords:

cancer, er stress, signaling, therapy, survival

Abstract

This article investigates the role of endoplasmic reticulum (ER) stress in the survival mechanisms of cancer cells. The research identifies key signaling pathways activated during ER stress that confer a survival advantage to cancer cells. By targeting these pathways, novel therapeutic strategies may be developed to enhance cancer treatment efficacy.

Author Biographies

Ashley Young

Ph.D. in Biochemistry
Ludwig Maximilian University of Munich
Geschwister-Scholl-Platz 1, 80539 München, Germany

Pat Young

Ph.D. in Oncology
Lviv National Medical University
Pekarska St, 69, Lviv, Ukraine, 79010

Kim Clark

Ph.D. in Cancer Biology
Stanford University
450 Serra Mall, Stanford, CA 94305, United States

References

Sharma, V. K., Marla, S., Zheng, W., Mishra, D., Huang, J., Zhang, W., ... & Cook, D. E. (2022). CRISPR guides induce gene silencing in plants in the absence of Cas. Genome Biology, 23(1), 6.

Published

2024-12-19

Issue

Section

Articles